Gurley suffered the ailment in last week's game versus the New Orleans Saints and didn't practice this week.
The veteran, who leads the Falcons in rushing this season, has racked up 610 yards and nine touchdowns through 10 games. Brian Hill is expected to carry the load at running back against the Raiders.
The Falcons also listed wide receiver Julio Jones as questionable with a hamstring issue.
Jones' issue also stems from the Saints game. The eight-time Pro Bowler missed most of the second half against New Orleans and didn't practice Friday after being limited Wednesday and Thursday.
The 31-year-old has amassed 677 yards and three scores on 45 receptions through eight appearances in 2020. He missed two games this season due to a hamstring injury.